COVID-19 Survivors Retain Immunity for a Minimum of One Year
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Understanding Immune Response in COVID-19 Survivors
When the coronavirus invades the body, the immune system reacts promptly, generating antibodies that attach to and neutralize the virus. This immune response has a "memory," allowing the body to recognize and combat the same pathogen more effectively during subsequent encounters.
Previously, studies raised questions about the longevity of immune protection against SARS-CoV-2, as observed antibody levels seemed to decline sharply within months post-recovery.
Recent Research Findings
Australian scientists have made significant strides in this area, demonstrating for the first time that individuals who have recovered from COVID-19 can depend on their immune system to prevent reinfection for at least eight months. This new evidence alleviates concerns regarding the durability of protection offered by newly developed COVID vaccines.
Menno van Zelm from Monash University, along with a collaborative team, shared their results in the esteemed journal, Science Immunology. The study monitored a group of 25 COVID-19 patients, collecting blood samples from the onset of infection up to 242 days after their diagnosis.
While the team observed the expected decline in antibody levels around two weeks after infection, they importantly identified memory B cells in the patients' blood using flow cytometry. These specialized cells target the spike and nucleocapsid proteins of SARS-CoV-2 and were found to persist for at least eight months, suggesting that the individuals would be protected from reinfection during this timeframe and potentially longer.
Importance of the Findings
“These findings are crucial as they confirm that individuals infected with the COVID-19 virus indeed retain immunity against both the virus and the associated disease,” stated van Zelm.
“This uncertainty has loomed over the potential protection offered by any COVID-19 vaccine, but this research brings genuine optimism that once vaccines are available, they will provide enduring protection.”
Sources: Science Immunology, EurekAlert!